Spot Diagnosis?

Thursday, November 4, 2010

Courtesy of C.S.Lee


Tan Yee Ping said...


Tommy said...


Tan Yee Ping said...


Neurofibromatosis type 1 = von Recklinghausen disease

Diagnostic criterias:

(dx = 2 out of 7)

- 6 or more café-au-lait macules over 5 mm in greatest diameter in pre-pubertal individuals and over 15 mm in greatest diameter in post-pubertal individuals

- 2 or more neurofibromas of any type or 1 plexiform neurofibroma

- Freckling in the axillary or inguinal regions

- Optic glioma

- 2 or more Lisch nodules (iris hamartomas)

- A distinctive osseous lesion such as sphenoid dysplasia or thinning of the long bone cortex with or without pseudarthrosis

- A first degree relative (parent, sibling, or offspring) with NF-1 by the above criteria